Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet

New England Journal of Medicine Volume 359:229-241 July 17, 2008 Number 3 The criteria for eligibility were an age of 40 to 65 years and a body-mass index of at least 27, or the presence of type 2 diabetes or coronary heart disease, regardless of age and BMI. Conclusions Mediterranean and low-carbohydrate diets may be effective alternatives to low-fat diets. The more favorable effects on lipids (with the low-carbohydrate diet) and on glycemic control (with the Mediterranean diet) suggest that personal preferences and metabolic considerations might inform individualized tailoring of dietary interventions.