Severe obstructive sleep apnea almost tripled stroke risk in men, data from a prospective cohort study showed.
Among men with mild or moderate apnea, each one-unit increase in the obstructive apnea hypopnea index (OAHI) raised stroke risk by 6%. Obstructive sleep apnea did not have a significant association with stroke risk in women, investigators reported online in the American Journal of Respiratory and Critical Care Medicine.
"This study provides compelling evidence based on eight years of prospective data from a large, geographically diverse community-based cohort of middle-age and older adults that modest to severe levels of sleep apnea increase risk of stroke in men, suggesting the need to evaluate the role of sleep apnea treatment in ameliorating stroke risk," Susan Redline, MD, of Case Western Reserve University in Cleveland, and colleagues concluded.
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