Blood levels of epilepsy drugs in nursing home residents can fluctuate wildly for no apparent reason, a researcher said here.
Serum concentrations of carbamazepine within individual patients varied from one measurement to the next by as much as 260%, and valproate levels showed swings of up to 460%, according Ilo Leppik, MD, of the University of Minnesota.
He reported the findings of a study of 44 nursing home residents at the American Academy of Neurology annual meeting.
In a separate presentation, Leppik also reported data indicating that new-onset seizures are twelve times as common in nursing home residents as in the community-dwelling elderly.
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