Certain clinical features such as polyarthritis and elevated erythrocyte sedimentation rate lessen the likelihood that patients with psoriatic arthritis will achieve sustained minimal disease activity, an observational cohort study suggested.
Multivariate logistic regression analysis determined that the odds ratio for minimal disease activity among patients with more than four tender or swollen joints was 0.296 (95% CI 0.171 to 0.511, P<0.0001), according to Laura C. Coates, MBChB, of the University of Leeds in England, and colleagues.
And the odds ratio for patients with elevated erythrocyte sedimentation rate -- signaling ongoing inflammatory activity -- was 0.546 (95% CI 0.326 to 0.914, P=0.02), the researchers reported in the July Arthritis Care Research.
A group of researchers recently developed a new definition of minimal disease activity in psoriatic arthritis that encompasses both remission and low disease activity.
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