Showing posts with label Psoriasis. Show all posts
Showing posts with label Psoriasis. Show all posts
Wednesday, May 11, 2011
Sunday, July 18, 2010
Polyarthritis, ESR Predict Psoriatic Arthritis Outcome from MedPage Today
By Nancy Walsh, Staff Writer, MedPage Today
Certain clinical features such as polyarthritis and elevated erythrocyte sedimentation rate lessen the likelihood that patients with psoriatic arthritis will achieve sustained minimal disease activity, an observational cohort study suggested.
Multivariate logistic regression analysis determined that the odds ratio for minimal disease activity among patients with more than four tender or swollen joints was 0.296 (95% CI 0.171 to 0.511, P<0.0001), according to Laura C. Coates, MBChB, of the University of Leeds in England, and colleagues.
And the odds ratio for patients with elevated erythrocyte sedimentation rate -- signaling ongoing inflammatory activity -- was 0.546 (95% CI 0.326 to 0.914, P=0.02), the researchers reported in the July Arthritis Care Research.
A group of researchers recently developed a new definition of minimal disease activity in psoriatic arthritis that encompasses both remission and low disease activity.
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Certain clinical features such as polyarthritis and elevated erythrocyte sedimentation rate lessen the likelihood that patients with psoriatic arthritis will achieve sustained minimal disease activity, an observational cohort study suggested.
Multivariate logistic regression analysis determined that the odds ratio for minimal disease activity among patients with more than four tender or swollen joints was 0.296 (95% CI 0.171 to 0.511, P<0.0001), according to Laura C. Coates, MBChB, of the University of Leeds in England, and colleagues.
And the odds ratio for patients with elevated erythrocyte sedimentation rate -- signaling ongoing inflammatory activity -- was 0.546 (95% CI 0.326 to 0.914, P=0.02), the researchers reported in the July Arthritis Care Research.
A group of researchers recently developed a new definition of minimal disease activity in psoriatic arthritis that encompasses both remission and low disease activity.
Continue Reading
Tuesday, March 9, 2010
Psoriasis Comorbidity Increases over Time - MedPage Today
Patients with psoriasis have multiple comorbid conditions that tend to worsen over time, data from a review of medical records showed.
At baseline, psoriasis patients had significantly higher rates of hypertension than non-psoriasis controls (14.9% versus 11.9%, P<0.0001), cardiovascular disease (CVD)(3.9% versus 3.1%, P=0.0151), depression (3.7% versus 2.8%, P=0.0077), diabetes (6.3% versus 5.0%, P=0.0471), and hyperlipidemia (15.2% versus 11.5%, P<0.0001).
Psoriasis patients also had a numerically greater prevalence of obesity (0.6% versus 0.2%), and the differences between the two groups increased during four years of follow-up, researchers reported at the American Academy of Dermatology meeting here.
Differences increased the most for depression, hyperlipidemia, and obesity.
"The trends [are] all going directionally in the same way, and the point spread between the groups continues to widen over time," Alexa Kimball, MD, of Harvard, told colleagues.
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