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Drugs intended to prevent osteoarthritis of the knee can realistically be cost-effective only if the annual expense per patient is substantially less than $1,000, researchers said here.
The limit was identified by computer modeling using multiple data inputs and the World Health Organization's reference standard for cost-effectiveness of $144,000 per quality-adjusted life-year (QALY) in the U.S., said Elena Losina, PhD, of Brigham and Women's Hospital in Boston.
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